Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Rat Ciliary Neurotrophic Factor
                
(Rat CNTF)
                
                

                
92125ES08
                
                

                
5 μg
                
                

                
815.00
                
            
            

                

                
92125ES60
                
                

                
100 μg
                
                

                
7865.00
                
            
            

                

                
92125ES76
                
                

                
500 μg
                
                

                
20425.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Ciliary neurotrophic factor (CNTF) is one of a small number of proteins with neurotrophic activities distinct from nerve growth factor (NGF). The cDNA for human CNTF encodes a 200 amino acid residue polypeptide that lacks a signal sequence. Recombinant human CNTF containing 200 amino acids and it shares 82% and 83% a.a. sequence identity with mouse and rat CNTF. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition, CNTF is useful for treatment of motor neuron disease and it could reduce food intake without causing hunger or stress. CNTF is structurally related to IL-6, IL-11, LIF and OSM. Among factors belonging to the CNTF family, CNTF, leukemia inhibitory factor, cardiotrophin-1, and oncostatin M induced a strong promyelinating effect. 
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
ciliary neurotrophic factor, CNTF, HCNTF
                
            
            

                

                
Accession
                
                

                
P20294
                
            
            

                

                
GeneID
                
                

                
25707
                
            
            

                

                
Source
                
                

                
E.coli-derived rat CNTF, Ala2-Met200.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 22.7 kDa.
                
            
            

                

                
AA Sequence
                
                

                
AFAEQTPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNINLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LMLQVSAFAY QLEELMVLLE QKIPENEADG MPATVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HQMGISALES HYGAKDKQM
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
>95% by SDS-PAGE and HPLC analyses.
                
            
            

                

                
Biological Activity
                
                
TUNEology 波长可调检测卡盒-->